地佐辛持续静脉泵注对重症监护室高龄髋部手术患者睡眠质量的影响

The Effect of Continuous Intravenous Infusion of Dezosin on Sleep Quality in Elderly Patients Undergoing Hip Surgery in the Intensive Care Unit

目的:分析地佐辛持续静脉滴注对重症监护室(ICU)高龄患者髋部手术后早期镇痛效果和睡眠质量的影响。方法:选取2023年1月至2024年1月烟台市蓬莱人民医院重症医学科收治的高龄髋部手术患者80例作为研究对象,按照随机数字表法分为对照组和观察组,每组40例。对照组给予氟比洛芬酯静脉注射镇痛处置,观察组给予氟比洛芬酯静脉注射联合地佐辛持续静脉泵注镇痛处置。采用匹兹堡睡眠质量指数(PSQI)比较2组患者睡眠质量的差异,采用视觉模拟评分法(VAS)比较2组患者干预前后疼痛感受的差异,并比较2组患者术后谵妄发生率及手术当天睡眠减少的患者比例。结果:干预后,观察组PSQI评分、VAS评分显著低于对照组,观察组患者术后谵妄发生率显著低于对照组,手术当天睡眠减少2 h与3 h的患者总构成比率显著低于对照组,差异均有统计学意义(均P<0.05)。结论:地佐辛持续静脉滴注在降低ICU高龄患者髋部手术后谵妄发生风险及协助患者获得理想的早期镇痛效果与睡眠质量中应用效果显著,能够有效缓解患者的疼痛感受,提高睡眠质量,值得临床推广应用。

Objective:To analyze the effects of continuous intravenous infusion of Dezosin on early postoperative analgesia and sleep quality in elderly patients undergoing hip surgery in the intensive care unit(ICU).Methods:A total of 80 elderly hip surgery patients admitted to the Department of Critical Care Medicine at Penglai People′s Hospital in Yantai City from January 2023 to January 2024 were selected as the study subjects.They were randomly divided into a control group and an observation group,with 40 cases in each group,using a random number table method.The control group received intravenous injection of flurbiprofen axetil for analgesic treatment,while the observation group received intravenous injection of flurbiprofen axetil combined with continuous intravenous pumping of dexamethasone for analgesic treatment.The Pittsburgh Sleep Quality Index(PSQI)was used to compare the differences in sleep quality between two groups of patients.The Visual Analog Scale(VAS)was used to compare the differences in pain perception between the two groups before and after intervention.The incidence of postoperative delirium and the proportion of patients with reduced sleep on the day of surgery were also compared between the two groups.Results:After intervention,the PSQI score and VAS score of the observation group were significantly lower than those of the control group.The incidence of postoperative delirium in the observation group was significantly lower than that of the control group.The total proportion of patients with reduced sleep for 2 and 3 hours on the day of surgery was significantly lower than that of the control group,and the differences between the two groups were statistically significant(P<0.05).Conclusion:Continuous intravenous infusion of Dezosin has a significant effect in reducing the risk of postoperative delirium in elderly ICU patients undergoing hip surgery and assisting them in achieving ideal early analgesic effects and sleep quality.It can effectively alleviate patient pain and improve sleep quality,and is worthy of clinical promotion and application.