胰体尾切除术后发生胃排空延迟的危险因素分析

Analysis of risk factors for delayed gastric emptying after distal pancreatectomy

目的探讨胰体尾切除术(DP)后发生胃排空延迟(DGE)的危险因素。方法回顾性分析2015年6月至2023年6月于扬州大学附属医院肝胆外科接受DP的75例患者的临床资料,采用单因素及多因素Logistic回归模型分析DGE发生的独立危险因素。结果75例患者中有16例(21.3%)术后发生DGE,其中A级12例(16.00%),B级3例(4.00%),C级1例(1.33%)。单因素分析结果显示,DGE组与非DGE组的术后腹腔出血、术后B级/C级胰瘘、术后腹腔感染、术后乳糜瘘占比比较,差异具有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,术后B级/C级胰瘘是DP术后发生DGE的独立危险因素(P<0.05)。结论术后B级/C级胰瘘是DP术后发生DGE的独立危险因素,围手术期避免胰瘘的发生有助于降低DGE的发生率。

Objective To investigate the risk factors for delayed gastric empting(DGE)after distal pancreatectomy(DP).Methods The clinical data of 75 patients who underwent DP in hepatobiliary surgery department of Affiliated Hospital of Yangzhou University from June 2015 to June 2023 were retrospectively analyzed.Univariate and multivariate Logistic regression models were used to analyze the independent risk factors of DGE.Results Of the 75 patients,16 cases(21.3%)had postoperative DGE,including 12 cases(16.00%)in grade A,3 cases(4.00%)in grade B,and 1 case(1.33%)in grade C.Univariate analysis results showed that there were statistically significant differences in proportions of postoperative abdominal bleeding,postoperative grade B/C pancreatic fistula,postoperative abdominal infection and postoperative chylous fistula in the DGE group and the non-DGE group(P<0.05).Multivariate Logistic regression analysis results showed that postoperative grade B/C pancreatic fistula was an independent risk factor for DGE after DP(P<0.05).Conclusion Postoperative grade B/C pancreatic fistula is an independent risk factor for DGE after DP.Avoiding pancreatic fistula during perioperative period can help reduce the incidence of DGE.