新冠疫情對澳門放療患者治療中斷的影響和劑量補償

Impact of COVID-19 on treatment interruption and dose compensation for radiotherapy patients in Macao

目的回顧性分析本中心放療患者在澳門疫情防控過渡期第二階段治療中斷及劑量補償的實施。方法收集2022年12月14日~2023年1月8日放療患者的資料,包括診斷,病理類型,治療目的,放療中斷次數,放療中斷時間,補量措施和療程延長時間等,分析患者的臨床治療參數。結果2022年12月14~2023年1月8日,本中心共74例患者接受放療,其中41例出現了非計劃放療中斷,佔55%。中斷患者中,20例接受了補量放療,佔51%。經補量後,治療延長時間為7±4(-2-14)天。1例患者提前2天完成治療,1例患者按時完成治療,3例患者治療延長時間控制在3天内,11例患者治療延長時間控制在1週内,全部補量患者治療延長時間控制在2週内。結論疫情增強了醫務人員對療程中斷和劑量補償的重視。劑量補償是減少放療療程延長的有效方法。

Objective To retrospectively analyze the treatment interruption and dose compensatory delivery of RT patients in our center during the second phase of the transition period for epidemic prevention and control in Macao.Methods Data of radiotherapy patients were collected from Dec 14th 2022 to Jan 8th 2023,including diagnosis,pathological type,treatment purpose,number of radiotherapy interruptions,radiotherapy interruption time,dose compensation and treatment course extension time and analyze the patient's tumor and treatment-related characteristics.Results From Dec 14th 2022 to Jan 8th 2023,a total of 74 patients received radiotherapy in our center,of which 41 patients had unplanned radiotherapy interruptions,accounting for 55%.Among the interrupted patients,20 received dose compensation,accounting for 51%.After compensation,the treatment extension time is 7±4(-2-14)days.One patient completed treatment 2 days in advance,1 patient completed treatment on time,3 patients'treatment extension time were controlled within 3 days,11 patients'treatment extension time were controlled within 1 week,and all compensated patients'treatment extension time were controlled within 2 weeks.Conclusion The epidemic has heightened medical staff's caution on treatment interruption and dose compensation.Dose compensation is an effective method to reduce the prolongation of radiotherapy courses.