阻塞性睡眠呼吸暂停增加脑血管病发病风险的研究进展

Research progress on obstructive sleep apnea increasing the risk of cerebrovascular disease

阻塞性睡眠呼吸暂停(OSA)是指在每晚睡眠过程中因反复上气道狭窄、塌陷、阻塞,呼吸暂停频繁发作从而使机体发生一系列病理生理改变的临床综合征。研究显示OSA是脑血管病的独立危险因素,并增加脑血管病的发病、复发、残疾及死亡风险。文章就OSA增加脑血管病发病风险的病理生理机制及临床研究进展进行综述。

Obstructive sleep apnea(OSA)is a clinical syndrome that presents with repeated upper airway stenosis,collapse,obstruction and frequent episodes of apnea during sleep causing a series of pathophysiological changes in the body.Studies have shown that OSA,as an independent risk factor,increases the occurrence and recurrence of cerebrovascular disease,which may lead to disability or death of patients.This article reviews the pathophysiological mechanism of OSA increasing the risk of cerebrovascular disease and related clinical research progress.