乳腺癌新辅助全身治疗后保留腋窝的研究进展

Axilla-conserving therapy in breast cancer patients after neoadjuvant systemic therapy:a literature review

乳腺癌新辅助全身治疗的有效率提高,使患者的腋窝治疗朝着降低治疗强度、保留腋窝的方向发展。尤其对于新辅助治疗后腋窝淋巴结降期的患者,豁免腋窝淋巴结清扫成为可能。但腋窝放疗能否取代腋窝淋巴结清扫仍有待进一步研究。另外,如何对腋窝转移淋巴结能达到病理完全缓解的患者进行预测,以挑选出能够豁免腋窝手术的人群也是临床关注的焦点。本文对乳腺癌新辅助全身治疗后保留腋窝的研究进展进行综述。

With the development of effective neoadjuvant systemic therapy for breast cancer,there is a trend towards reducing the surgical treatment intensity and conserving the axilla.It is possible to omit axillary lymph node dissection for patients with axillary downstaging after neoadjuvant systemic therapy.However,whether axillary radiotherapy can replace axillary lymph node dissection remains to be further studied.The complete omission of axillary surgery is also the focus of clinical research for patients who can be predicted to achieve axillary pathological complete response.In this article,we provide an overview of recent research progress in axilla-conserving therapy for breast cancer patients after neoadjuvant systemic therapy.