老年2型糖尿病患者结肠腺瘤性息肉发病的危险因素研究

Analysis on the high-risk factors of colonic adenomatous polyps in elderly patients with type 2 diabetes

[目的]探讨老年2型糖尿病患者结肠腺瘤性息肉发病的危险因素,以期为临床诊治提供参考。[方法]回顾性分析112例老年2型糖尿病患者临床资料,根据是否伴结肠腺瘤性息肉分为腺瘤组(57例)与无腺瘤组(55例)。单因素和多因素Logistic回归分析影响老年2型糖尿病患者结肠腺瘤性息肉发病的高危因素。[结果]单因素分析显示,腺瘤组与无腺瘤组在胆囊疾病、长期饮酒史、胰岛素使用及幽门螺杆菌感染上相比,差异有统计学意义(P<0.05)。将上述有差异的单因素分析进行多因素Logistic回归分析显示,胆囊疾病、长期饮酒史、胰岛素使用及幽门螺杆菌感染为老年2型糖尿病患者结肠腺瘤性息肉发病的高危因素。[结论]老年2型糖尿病患者结肠腺瘤性息肉发病率较高,且其高危因素包括胆囊疾病、长期饮酒史、胰岛素使用及幽门螺杆菌感染,值得临床注意。

[Objective]To investigate the risk factors of colorectal adenomatous polyps in elderly patients with type 2 diabetes mellitus,so as to provide reference for clinical diagnosis and treatment.[Methods]The clinical data of 112 elderly patients with type 2 diabetes who underwent colonoscopy were retrospectively analyzed,and they were divided into adenoma group(57 cases)and non-adenomatous group(55 cases)according to whether they had colorectal adenomatous polyps.Univariate and multivariate logistic regression analysis on the risk factors of colorectal adenomatous polyps in elderly patients with type 2 diabetes mellitus.[Results]Univariate analysis showed that there were significant differences in gallbladder disease,long-term drinking history,insulin use and Helicobacter pylori infection between the adenoma group and the non-adenoma group(P<0.05).Multivariate logistic regression analysis showed that gallbladder disease,long-term drinking history,insulin use and Helicobacter pylori infection were high risk factors for colorectal adenomatous polyps in elderly type 2 diabetes patients.[Conclusion]The incidence of colorectal adenomatous polyps in elderly patients with type 2 diabetes mellitus is high,and its risk factors include gallbladder disease,long-term drinking history,insulin use and Helicobacter pylori infection,which deserves clinical attention.