肝癌患者肝动脉化疗栓塞术后恶心和呕吐的危险因素及评估工具研究进展

Research progress in risk factors and evaluation tools for nausea and vomiting after hepatic artery chemoembolization in liver cancer patients

原发性肝癌是我国常见恶性肿瘤,在肿瘤致死病因中居于第二位,严重威胁国民的生命健康。肝动脉化疗栓塞(TACE)是无法通过手术根治的肝癌患者的首选治疗方法,对于延长患者生命具有重要意义。但TACE术后的高恶心呕吐发生率,是导致患者治疗依从性下降的重要原因,严重影响患者的生活质量和介入治疗的效果。本文对国内外TACE术后患者恶心和呕吐的特点、危险因素、评估工具进行了综述,以期对TACE术后恶心和呕吐进行早期识别及有效的干预提供依据。

Primary liver cancer(PLC)is a common malignant tumor in China.It ranks second in the cause of tumor mortality and it is a serious threat to the lives and health of people.Transcatheter arterial chemoembolization(TACE)is the preferred treatment for patients with HCC who cannot be surgically cured,which is of great significance for prolonging the patient's life.However,the incidence of nausea and vomiting after TACE is very high,which is an important reason for the decline of patient treatment compliance,which seriously affects the quality of life and the effect of interventional therapy.This paper reviews the domestic and abroad literature concerning the nausea and vomiting in patients after TACE,focusing on the clinical features of nausea and vomiting,the risk factors and the assessment tools,so as to provide a scientific basis for clinical early identification and effective intervention of nausea and vomiting after TACE.