胆道闭锁自体肝生存相关危险因素及预测模型研究进展

Research advances of risk factors and predictive models associated with native liver survival in biliary atresia

胆道闭锁(biliary atresia,BA)是一种严重的婴幼儿肝胆系统疾病,是儿童肝移植最常见的指征。对患儿进行预后评估及选择个性化治疗对于BA的治疗至关重要,目前尚没有规范化的BA预后预测模型对BA患儿进行有效的预后评估。本文就胆道闭锁葛西术后自体肝生存的预后危险因素及相关预测模型的研究新进展进行综述。

As a severe disease of hepatobiliary system in infants and toddlers,biliary atresia(BA)is thes most common indication for liver transplantation(LT).Prognostic assessments and individualized treatments are crucial for managing BA.Currently there is still no standardized prognostic prediction model for effectively assessing the prognosis of BA patients.This review summarized the latest advances of risk factors and predictive models for native liver survival(NLS)after Kasai procedure.