四川省2019-2022年环境污水脊髓灰质炎病毒监测

Monitoring poliovirus in environmental sewage in Sichuan province,2019-2022

目的评估四川省环境污水脊髓灰质炎(脊灰)病毒现状和传播风险。方法2019年8月-2022年12月在四川省6个监测点采集环境污水样本,进行脊灰病毒分离和鉴定。结果共采集环境污水样本90份,分离到脊灰病毒105株、非脊灰肠道病毒160株。所有脊灰病毒分离株均鉴定为脊灰疫苗相似株,其中Ⅰ型、Ⅱ型、Ⅲ型、Ⅰ+Ⅲ型PV分别占18.10%(19株)、0.00%(0株)、81株(77.14%)、5株(4.76%)。结论监测地区环境污水未发现脊灰野病毒或疫苗衍生脊灰病毒,监测结果为四川省继续维持无脊灰状态提供了补充证据。

Objective To evaluate for presence and transmission risk of polioviruses using environmental sewage surveillance in Sichuan province.Methods We obtained environmental sewage samples from six monitoring sites in Sichuan from August 2019 to December 2022 for poliovirus isolation and identification.Results From 90 environmental sewage samples,105 poliovirus strains and 160 non-polio enterovirus strains were isolated.All poliovirus isolates were Sabin-like strains,among which typeⅠ,typeⅡ,typeⅢ,and mixed typeⅠ+Ⅲpolioviruses accounted for 18.10%(19 strains),0.00%(0 strains),77.14%(81 strains),and 4.76%(5 strains),respectively.Conclusions No wild poliovirus or vaccine-derived polioviruses were found in environmental sewage monitoring areas.These result provide supportive evidence of continued maintenance of polio-free status in Sichuan.