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TFE3肾细胞癌的超声表现及其在分期中的价值

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摘要 目的探讨TFE3肾细胞癌的超声表现及其在分期中的诊断价值。方法回顾性分析2014年5月至2021年6月北京大学第三医院收治的19例TFE3肾细胞癌患者的临床特点和超声表现,并以病理为金标准,将本组肿瘤按最大径分为≤7 cm与>7cm组,对比两组超声表现的不同,采用Spearman相关分析对肿瘤大小与形态、内部回声、边缘、血流分级、有无肾积水、肾周侵犯、有无转移等情况进行比较。结果本组19例均为单发、实性、圆形或椭圆形,多为边界清晰,内部回声多不均匀,以高回声和等回声为主,部分伴囊泡或钙化,血流信号多不丰富。≤7 cm组与>7 cm组之间肾静脉侵犯和远处转移发生率比较,差异有统计学意义(P<0.05)。spearman相关分析显示,肿瘤最大上下径分别与肿瘤的边缘分叶(r=0.688,P=0.001)、肾静脉癌栓(r=0.557,P=0.013)、腹膜后淋巴结转移(r=0.475,P=0.040)以及远处转移(r=0.625,P=0.002)具有相关性。病理证实的肾窦侵犯与肾积水(r=0.774,P<0.001)、凸向肾窦的高度(r=0.541,P=0.017)、肿瘤垂直肾实质厚度(r=0.559,P=0.013)及肿瘤垂直肾实质的厚度与邻近正常肾实质的厚度比值(r=0.538,P=0.017)具有相关性。当肿物凸向肾窦高度为1.75 cm时,AUC下面积为0.821,诊断肾窦侵犯的灵敏度和特异度分别为100%和75%。结论TFE3肾细胞癌超声表现通常不具有特异性,需结合临床特点,当肿瘤凸向肾窦高度≥1.75 cm时,可作为预测肾窦侵犯的最佳界值。
出处 《安徽医学》 2024年第7期885-889,共5页 Anhui Medical Journal
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