爆炸致创伤性颅脑损伤后神经行为学改变的研究进展

Research progress on neurobehavioral changes after traumatic brain injuries caused by explo-sion

随着世界军事格局的变动与社会经济发展的失衡,爆炸性事件越来越多,爆炸致创伤性颅脑损伤(bTBI)在现代战争及爆炸事故中常见。近年来,TBI后认知功能障碍研究较多,bTBI的各种基础与临床研究也有较多报道。bTBI后一般存在各种功能障碍,主要表现为意识障碍、认知障碍、肢体运动障碍和精神心理障碍,并可在较长时间存在,严重影响患者生活质量及社会参与程度,并给患者家庭及社会造成沉重负担。本文对bTBI流行病学特征与行为学研究结果进行综述与分析,为进一步深入开展研究bTBI神经行为学异常提供新的思路和方向。

With changed military patterns of the world and imbalanced social and economic development,there are more and more explosive events.Blast-induced traumatic brain injury(bTBI)is one of the common casual-ties in modern warfare and explosion accidents.In recent years,there have been many studies on cognitive dysfunc-tion after TBI,and various basic and clinical reports on bTBI.Generally,various dysfunctions may occur after bTBI,which mainly manifest as consciousness disorder,cognitive disorder,limb movement disorder,and mental and/or psy-chological disorder and can exist for a long time.These seriously affect the quality of life and social participation of patients and cause a heavy burden on their families and society.This article reviews and analyzes the neurobehavioral epidemiology and behavioral test results after bTBI,and provides new ideas and directions for further research on neurobehavioral abnormalities following bTBI.