摘要
目的探讨40 m高压空气暴露对潜水员肱动脉功能的影响。方法选择5名潜水员作为受试者。所有受试者均接受最高压力为40 m的高压空气暴露,高气压暴露时间共计190 min。采用多普勒超声诊断仪检测高气压暴露前后受试者的肱动脉直径、收缩峰值流速(SPV)、阻力指数(RI),计算血流介导的血管舒张(FMD),评价高气压暴露对肱动脉功能的影响。结果与高气压暴露前相比,高气压暴露后肱动脉直径呈下降趋势(P>0.05),RI和FMD稍有升高(P>0.05),而SPV下降(P<0.05)。结论40 m高压空气暴露可导致肱动脉收缩,血流阻力增加、流速下降,但对肱动脉的功能影响较小,FMD变化不显著。
Objective To investigate the effect of 40 m hyperbaric air exposure on brachial artery function of divers.Methods Five divers were enrolled and exposed to hyperbaric air with a maximum pressure of 40 m for a total of 190 min.The brachial artery diameter,systolic peak velocity(SPV)and resistance index(RI)were measured by Doppler ultrasonography before and after hyperbaric air exposure,and flow-mediated dilation(FMD)was calculated to evaluate the effect of hyperbaric air exposure on brachial artery function.Results Compared with before hyperbaric air exposure,the brachial artery diameter was decreased(P>0.05),RI and FMD were increased slightly(P>0.05),while SPV was decreased significantly(P<0.05)after hyperbaric air exposure.Conclusion Exposure to hyperbaric air at 40 m can lead to brachial artery contraction,increase resistance,and decrease flow velocity,but it has a slight impact on the brachial artery function,with no significant change in FMD.
作者
刘文武
张婷婷
文宇坤
俞旭华
徐佳骏
王世锋
LIU Wenwu;ZHANG Tingting;WEN Yukun;YU Xuhua;XU Jiajun;WANG Shifeng(Department of Diving and Hyperbaric Medical Research,Naval Medical Center,Naval Medical University(Second Military Medical University),Shanghai 200433,China;Department of Research,Naval Medical Center,Naval Medical University(Second Military Medical University),Shanghai 200433,China)
出处
《海军军医大学学报》
CAS
CSCD
北大核心
2024年第7期896-899,共4页
Academic Journal of Naval Medical University
基金
上海市市级科技重大项目(2023SHZDZX02-030702).