基于3D-Slicer上颌骨自体骨移植供骨量及其相关因素分析

A study on the potential donor sites and related factors of maxilla for autogenous bone grafting based on 3D-Slicer

目的:通过3D-Slicer软件三维重建并测量上颌骨前鼻棘、硬腭、上颌结节等区域潜在取骨量及骨密度,为上颌骨作为自体骨移植潜在取骨位点的临床应用提供参考。方法:应用3D-Slicer软件对129例颅颌面CBCT数据进行三维重建,测量前鼻棘、硬腭、上颌结节的潜在取骨量、骨密度。对其在不同性别、年龄人群中的特点进行分析比较。结果:1.硬腭区域可取骨量最大(1512.31±71.93 mm^(3)),前鼻棘区可取骨量最小(444.74±17.49 mm^(3))。前鼻棘取骨区域的骨密度最高(HU:601.28±7.76),上颌结节取骨区域的骨密度最低(HU:259.84±5.44)。2.男性前鼻棘、硬腭、上颌结节区域的潜在取骨体积均大于女性。3.中老年组(≥40岁)在前鼻棘区域的潜在取骨体积大于青年组(<40岁)。结论:前鼻棘、硬腭、上颌结节可分别作为颌骨小型、中型骨缺损的口内自体骨移植取骨位点。

Objective:The aim of this research was to use 3D-Slicer software to reconstruct and analyze the bone volume and density available in the anterior nasal spine,hard palate,and maxillary tuberosity in order to investigate the potential of maxilla as a source of autologous bone grafts.Methods:129 CBCT scans were reconstructed and evaluated by 3D-Slicer software,to analyze potential available bone volume and density of the bone in the anterior nasal spine,hard palate,and maxillary tuberosity.Correlations of those parameters with gender and age were analyzed.Results:1.The maximal bone volume which could be obtained from the palate was 1512.31±71.93 mm^(3),while that from the anterior nasal spine was 444.74±17.49 mm^(3).The bone density in the anterior nasal spine is highest(HU:601.28±7.76),while the bone density in the maxillary tuberosity is lowest(HU:259.84±5.44).2.The potential bone volume in anterior nasal spine,palate,and maxillary tuberosity in male was greater than that in female.3.The potential bone volume in the anterior nasal spine of the middle-aged and elderly group(≥40 years old)is greater than that of the young group(<40 years old).Conclusion:Anterior nasal spine,hard palate,and maxillary tuberosity can be used as intraoral autologous donor sites for small and medium-size bone defects.