摘要
子痫前期(preeclampsia)是一种起源于胎盘功能障碍,以母体内皮功能障碍为发病核心,以新发高血压和蛋白尿为主要症状的妊娠期疾病。甲状腺相关激素对女性的生殖代谢有重要作用,且妊娠期甲状腺疾病可导致多种不良妊娠结局。研究发现甲状腺相关激素与子痫前期密切相关。综述甲状腺相关激素参与子痫前期发病机制的途径及妊娠期甲状腺疾病与子痫前期的相关性,探究甲状腺相关激素在子痫前期发生发展中的作用。
Preeclampsia(PE)is a pregnancy disorder originating from placental dysfunction,with maternal endothelial dysfunction at the core of pathogenesis.The main symptoms of PE are new-onset hypertension and proteinuria.Thyroid-related hormones have an important impact on reproduction and metabolism in women,while thyroid disorders can lead to a variety of adverse pregnancy outcomes.Thyroid-related hormones have been found to be strongly associated with PE.This paper will outline the pathways of thyroid-related hormones implicated in the pathogenesis of PE and examine the relationship between thyroid dysfunction and PE during pregnancy,with the aim of elucidating the potential role of thyroid-related hormones in the development and progression of PE.
作者
柳芳蕾
冯晓玲(审校)
LIU Fang-lei;FENG Xiao-ling(Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China;The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China)
出处
《国际生殖健康/计划生育杂志》
CAS
2024年第4期348-352,共5页
Journal of International Reproductive Health/Family Planning
关键词
孕妇
甲状腺素
甲状腺疾病
先兆子痫
妊娠并发症
胎盘
Pregnant women
Thyroxine
Thyroid diseases
Pre-eclampsia
Pregnancy complications
Placenta