维生素D缺乏对育龄期女性健康的影响

Effects of vitamin D deficiency on the health of women of reproductive age

维生素D是一种脂溶性维生素,主要功能是促进小肠黏膜细胞对钙和磷的吸收,提高血钙和血磷的浓度,有利于新骨生成和钙化。此外,维生素D还有促进皮肤细胞生长、分化及调节免疫功能的作用。近年来,维生素D与内分泌系统之间的关系日益受到关注,尤其在女性生殖健康方面。维生素D缺乏可导致诸多不良妊娠结局,并增加多囊卵巢综合征及子宫内膜异位症的发生风险。孕妇维生素D缺乏亦可能增加妊娠期糖尿病及子痫前期的发生风险。妊娠期补充维生素D可降低不良妊娠结局的发生风险,预防子痫前期,并有望改善妊娠期糖尿病的病情。维生素D与多种女性生殖系统疾病密切相关,在调节女性生殖健康方面发挥重要作用。

Vitamin D is a fat-soluble vitamin,which the main function is to promote the absorption of calcium and phosphorus by small intestinal mucosa cells,increase the concentration of blood calcium and phosphorus,conducive to new bone formation and calcification.In addition,vitamin D also promotes skin cell growth,differentiation and immune function regulation.In recent years,the relationship between vitamin D and endocrine system has received increasing attention,especially in the context of female reproductive health.Vitamin D deficiency is associated with many adverse pregnancy outcomes and an increased risk of polycystic ovary syndrome and endometriosis.Vitamin D deficiency in pregnant woman may also increase the risk of gestational diabetes and preeclampsia.Vitamin D supplementation during pregnancy may reduce the risk of adverse pregnancy outcomes,prevent preeclampsia,and is expected to improve the condition of gestational diabetes.Vitamin D is closely related to a variety of female reproductive system diseases and plays an important role in regulating female reproductive health.