从儿童期开始心血管疾病预防的研究进展

Research progress of cardiovascular disease prevention commencing in childhood

心血管疾病(CVD)造成了巨大的疾病负担,近年来儿童期在CVD的预防中地位凸显。前瞻性队列研究证据明确了儿童期的多种危险因素与成年期CVD的发生风险密切相关;同时,随机对照试验也取得了重要进展,表明儿童期的健康生活方式可以有效促进心血管健康。文章就目前儿童CVD危险因素的流行特征、与成年后CVD发生风险的关联以及在儿童期开展的干预研究进展进行综述,以期为从儿童期开始CVD预防提供科学参考。

Cardiovascular diseases(CVD)have imposed a substantial disease burden in China.Recently,the significance of childhood in CVD prevention has gained a significant attention.Prospective cohort studies have provided conclusive evidence that various risk factors during childhood are associated with the risk of CVD in adulthood.Furthermore,randomized controlled trials have made noteworthy advancements,demonstrating that healthy lifestyles during childhood could significantly promote cardiovascular health.The paper reviews the prevalence characteristics of CVD risk factors in Chinese children,the association with the risk of CVD development in adulthood and the progress of intervention research in childhood,in order to provide a scientific reference for the prevention of CVD from childhood.