基于“络损脉痹”理论辨治糖尿病周围神经病变思路探析

An Analysis on the Treatment of Diabetic Peripheral Neuropathy based on the Theory of“Collateral Damage and Pulse Arthralgia”

“络损脉痹”是糖尿病周围神经病变(DPN)的病机关键。气阴两虚、肝肾亏虚、湿热伤络、痰瘀阻络等是形成该病的主要原因。研究显示,养络通痹方药具有减轻炎症反应、修复神经功能、改善血液流变性、调节生长因子等作用,深入研究DPN“络损脉痹”的病因病机及养络通痹法的作用机理,对提高DPN的防治水平具有重要的临床意义。

“Collateral damage and pulse arthralgia”is the key pathogenesis of(DPN.)Qi-Yin Deficiency,deficiency of liver and kidney,dampness-heat injury of collaterals and phlegm stasis blocking collaterals are the main causes of this disease.Studies have shown that Yangluo Tongbi recipe has the functions of reducing inflammation,repairing nerve function,improving hemorrheology,regulating growth factors,etc.Thus,further research on the etiology and pathogenesis of“collateral-loss and arterial-obstruction”of DPN and the mechanism of Yangluo Tongbi method have important clinical significance for improving the prevention and treatment level of DPN.