溶胀法制备荧光微球研究进展

Research Progress on Fluorescent Microspheres Through Swelling Methods

溶胀法作为一种可调控性强、操作简单、实用性高的制备荧光微球的方法而被广泛应用。本文综述了利用溶胀法制备荧光微球的研究进展,阐述了溶胀法制备荧光微球的基本原理和步骤。进一步综述了溶胀过程中影响微球性能的常见因素,例如聚合物基质、荧光物质、溶胀剂的种类等,总结了溶胀法调控优化荧光微球的改进策略,对溶胀法制备荧光微球的应用前景进行了展望。

Swelling method is widely used as a method for preparing fluorescent microspheres with strong controlla⁃bility,simple operation and high practicability.This paper reviews the research progress of preparing fluorescent mi⁃crospheres by swelling method,expounds the basic principle and steps of preparing fluorescent microspheres by swelling method.It further summarizes the common factors affecting the performance of microspheres during swelling process,such as the types of polymer matrix,fluorescent substance and swelling agent.The improvement strategy of swelling method for optimization of fluorescent microspheres is summarized,and the application prospect of fluores⁃cent microspheres prepared by swelling method is prospected.