Risk factors of abnormal urinary albumin/ creatinine ratio in people with obesity

Objective To explore the clinical characteristics and risk factors of abnormal urinary albumin/creatinine ratio(UACR)in obese population.Methods Baseline data from 2011 to 2012 in Henan Sub-center of"Risk Evaluation of Cancers in Chinese Diabetic Individuals:A longitudinal(REACTION)study"were utilized and those of body mass index≥28 kg/m^(2) were screened.The patients were divided into UACR normal group and UACR abnormal group(101 pairs)upon being matched on a 1:1 basis by age and gender.Multivariate logistic regression analysis,receiver operating characteristic(ROC)curve,and restricted cubic spline(RCS)analysis were performed to explore the risk factors for abnormal UACR.Results Compared with the normal UACR group,the UACR abnormal group had a higher number of alcohol consumers,a higher prevalence of hypertension,elevated systolic blood pressure,and triglyceride(all P<0.05).Multivariate logistic regression analysis showed that alcohol consumption(P=0.008).