Pathological types and clinical features of unilateral primary aldosteronism.

Objective Toinvestigate the distribution of pathological types of unilateral primary aldosteronism,and to explore the clinical characteristics and prognosis of patients with different pathological types.Methods A total of 241 patients with unilateral primary aldosteronism who underwent adrenal surgery were included in this study.The clinical and postoperative follow-up data were collected,and the postoperative tissue sections were stained with HE and aldosterone synthase.According to the staining results,pathological types of 241 patients were classified,and the clinical characteristics and surgical prognosis of patients with unilateral primary aldosteronism were compared.Results According to the international histopathology consensus forunilateral primary aldosteronism,among 241 patients with unilateral primary aldosteronism,223 were classical(92.5%),17 were non-classical(7.1%),and 1 was aldosterone producing carcinoma(0.4%).Among classical cases,189 were aldosterone producing adenoma and 34 were aldosterone producing nodule.In the non-classical cases,8 cases were mnultiple aldosterone producing nodule and 9 cases were multiple aldosterone producing nodule.