Study on the correlation between sleep disturbances and cognitive impairment-associated cerebral small vascular disease in elderly people

Objective To investigate the clinical characteristics and correlation of sleep disturbances(SD)with cognitive impairment-associated cerebral small vascular disease(CSVD-CI)in elderly patients.Methods In this crosssectional study,261 elderly CSVD-CI patients admitted to the Department of Neurology,Second Hospital of Tianjin Medical University between December 2019 and December 2021 were continuously enrolled.The Pittsburgh Sleep Index Scale(PSQI)was used to evaluate the overall sleep quality.Those with a PSQI score≥7 were assigned to the CSVD-CI with sleep disturbances(CSVDCI CSVDCI-SD)group,while those with a PSQI score<7 were assigned to the CSVD-CI without SD(CSVD-CI-NSD)group.The Montreal Cognitive Assessment(MoCA)was used to evaluate the cognitive function of patients with CSVD-CI,and scores on the overall cognitive function and various cognitive domains were compared between the CSVD-CI-SD group and the CSVD-CI-NSD group.Results There were no significant differences between the CSVD-CI-SD group and the CSVD-CI-NSD group in sex ratio,age,education level and comorbidities(P>0.05).