摘要
Deaminase-based cytosine base editors(CBEs)and adenine base editors(ABEs)induce C-to-T and A-to-G transitions,respectively,enabling single-nucleotide variants(SNVs)in plants for research and crop enhancement(Li et al.,2023a).The C-to-G base editors(CGBEs)and A-to-Y base editors(AYBEs),developed by incorporating glycosylases with CBEs and ABEs,expand the repertoire of base editing products,allowing C-to-T/G and A-to-T/G transversions in plants(Li et al.,2023b,2023c;Sretenovic et a.,2021).
基金
supported by the National Key R&D Program of China(2021YFA1300404 to J.-K.Z.)
the National Natural Science Foundation of China(32188102 to J.-K.Z.)
the China Postdoctoral Science Foundation(BX20220098 and 2022M720973 to Y.T.)
the Hainan Seed Industry Laboratory(B22C1000P to Y.T.)
Nanfan special project,CAAS(ZDXM2314 to M.W.)。