基于CiteSpace可视化分析心脏骤停后脑损伤研究的现状和热点

The current state and hotspots of post-cardiac arrest brain injury:a visualization analysis based on CiteSpace

目的通过对心脏骤停后脑损伤研究的文献进行可视化分析,探究近10年心肺脑复苏的研究现状、热点和发展趋势。方法Web of Sciences(WOS)核心数据库中以“cardiac arrest OR resuscitation OR cardiopulmonary resuscitation”和“brain*OR neuro*”为主题词检索英文文献,采用CiteSpace 5.8.R3软件分析发文量高产的国家、机构、作者以及合作关系,对关键词进行共现、聚类和突现分析,绘制时线图和时区图。结果检索纳入2013年1月1日至2023年10月25日WOS核心数据库有效文献10867篇。发文量前3的国家依次为美国、中国和日本,其中,美国发文量最高,共3691篇,中介中心性0.47;发文量最高的作者是瑞典隆德大学的Hans Friberg,共110篇;关键词共现分析,频次最高前5个是心脏骤停、心肺复苏、复苏、存活、结局;关键词聚类共有4个标签,分别是“#0院外心脏骤停、#1创伤性脑损伤、#2目标温度管理和#3全脑缺血性损伤”;关键词突现分析,突现强度前5位是亚低温、心血管急诊护理、神经元特异性烯醇化酶、脑缺血、肾上腺素,出现年份最新的前5位是院外心脏骤停、心肺复苏、肾上腺素、昏迷、工作组。时线图和时区图显示,2017年后的研究方向集中在院外心脏骤停和创伤性脑损伤,新出现的高频关键词有体外膜肺、重症监护、危险因素、脑电图。结论院外心脏骤停、创伤性脑损伤、目标温度管理是近年来心肺脑复苏的研究热点,而体外膜肺、重症监护、脑电图将是研究发展趋势。

Objective This study examined the development trend and research hotspot of cardiopulmonary brain resuscitation in the last ten years by a visual analysis of the literature on postcardiac arrest brain injury.Methods English articles were acquired from the Web of Sciences(WOS)core database.CiteSpace 5.8.R3 software was used to analyze annual publications,countries,institutions,authors.We identified the trending research areas by analyzing collaborative networks,keywords cooccurrence,burst detection analysis,timeline and time-zone diagrams.Results The search included 10867 articles in the WOS core database from Jan 1,2013 to Oct 25,2023.In the last ten years,the top 3 nations were the United States,China,and Japan,with the United States having the most citation of 3691 and an centrality of 0.47.The author with the highest number of publications was Hans Friberg from Sweden.The top 5 most frequent keywords in WOS were cardiac arrest,cardiopulmonary resuscitation,resuscitation,survival,outcome.Keyword cluster analysis showed 4 clusters,including:#0 of-hospital cardiac arrest,#1 traumatic brain injury,#2 targeted temperature management,#3 global cerebral ischemia.Keyword burst showed that the top 5 ranked by strength are mild hypothermia,emergency cardiovascular care,neuron specific enolase,cerebral ischemia,epinephrine,and the top 5 ranked by the year of burst begins are out-of-hospital cardiac arrest,cpr,epinephrine,coma,and task force.The timeline and time zone charts indicated that,starting in 2017,the main fields of study concentration were traumatic brain injury and out-of-hospital cardiac arrest.Additionally,extracorporeal membrane,intensive care,risk factors,and electroencephalography were identified as new high-frequency keywords.Conclusions Over the past ten years,the research hotspots on post-cardiac arrest brain injury include out-of-hospital cardiac arrest,traumatic brain injury,and target temperature control.The research development trends will be extracorporeal membrane oxygenation,critical care,and EEG.