北京地区孕产妇TORCH血清流行病学调查研究

Epidemiological Investigation of TORCH Serum in Pregnant and Postpartum Women in Beijing Area

目的分析2018-2022年在该院就诊的孕产妇血清TORCH感染情况及流行特点。方法对2018-2022年在该院进行孕期筛查的女性共计27357例结果进行分析,按年龄段、年度进行分组,结果用SPSS软件进行统计分析。结果孕产妇TOX、RV、CMV、HSV-ⅡIgM的阳性率分别为0.03%、1.27%、1.86%和0.08%,IgG的阳性率分别为4.46%、90.31%、92.87%和4.49%。≥35岁高龄孕妇组CMV IgM、RV IgG抗体阳性率显著低于<35岁组,差异有统计学意义(均P<0.05),TOX IgG、HSV-ⅡIgG抗体阳性率显著高于<35岁组,差异有统计学意义(均P<0.05)。CMV IgG阳性率近几年呈递减趋势。结论高龄组CMV IgM、RV IgG抗体阳性率更低,TOX IgG、HSV-ⅡIgG抗体阳性率更高。CMV IgG阳性率有呈逐年下降趋势,RV IgG和HSV-ⅡIgG阳性率逐年上升。

Objective To analyze the serum TORCH infection status and epidemic characteristics of preg-nant and postpartum women who visited Peking University Third Hospital from 2018 to 2022.Methods A total of 27,357 women who underwent pregnancy screening in Peking University Third Hospital from 2018 to 2022 were analyzed,grouped by age and year,and the results were statistically analyzed using SPSS software.Results The positive rates of maternal TOX IgM,RV IgM,CMV IgM and HSV-ⅡIgM were 0.03%,1.27%,1.86%and 0.08%,and positive rates of IgG were 4.46%,90.31%,92.87%and 4.49%,respectively.The positive rates of CMV IgM and RV IgG in older pregnant women≥35 years old were significantly lower than those in<35 years old group,and the difference were statistically significant(P<0.05),and the positive rates of TOX IgG and HSV-ⅡIgG antibodies were significantly higher than those in<35 years old group,and the difference were statistically significant(P<0.05).Conclusion The positive rate of CMV IgM and RV IgG antibody is lower in the elderly group,and the positive rate of TOX IgG and HSV-ⅡIgG antibody is higher.The positive rate of CMV IgG decreased,that of RV IgG and HSV-ⅡIgG increased.