心电图aVR导联及血NT-proBNP、MHR与非ST段抬高型心肌梗死患者冠脉病变相关性研究

Correlation between aVR Lead of ECG,NT-proBNP and MHR and Coronary Artery Disease in Patients with Non-ST-segment Elevation Myocardial Infarction

目的分析心电图aVR导联及血氨基酸末端B型脑钠素原(NT-proBNP)、外周血单核细胞/高密度脂蛋白胆固醇比值(MHR)与非ST段抬高型心肌梗死患者冠脉病变(NSTEMI)的相关性。方法回顾性分析2020年1月至2022年12月在邹平市中心医院就诊的NSTEMI患者72例,依据患者冠脉病变支数给予分组,20例患者纳入单支病变组,27例患者纳入双支病变组,25例患者纳入三支病变组,比较各组患者心电图aVR导联及血NT-proBNP、MHR与NSTEMI的差异,并分析相关性。结果双支病变组、三支病变组血NT-proBNP、MHR高于单支病变组,三支病变组血NT-proBNP、MHR高于双支病变组,差异均有统计学意义(P<0.05)。QRS、ST段下移程度与NSTEMI患者冠脉病变支数呈正相关(P<0.05),ST段下移导联数、T波倒置与NSTEMI患者冠脉病变支数不具有相关性(P>0.05);血NT-proBNP、MHR与NSTEMI患者冠脉病变支数呈正相关(P<0.05)。结论QRS、ST段下移程度及血NT-proBNP、MHR与NSTEMI患者冠脉病变支数呈正相关。

Objective To analyze the correlation between aVR lead of the electrocardiogram(ECG),amino acid-terminal B-type brain natriuretic peptide(NT-proBNP),peripheral blood monocyte/high density lipoprotein cholesterol ratio(MHR),and coronary artery disease in patients with non-ST-segment elevation myocardial infarction(NSTEMI).Methods 72 non-NSTEMI patients diagnosed and treated in our hospital from January 2020 to December 2022 were selected and grouped according to the number of coronary lesion branches,while 20 patients were included in the single-vessel lesion group,27 patients were included in the double-vessel lesion group,and 25 patients were included in the triple-vessel lesion group.We compared the differences between ECG AVR lead,blood NT-proBNP,MHR,and NSTEMI,and the correlation was analyzed.Results The blood NT-proBNP and MHR in the double-vessel lesion group and the triple-vessel lesion group were higher than those in the single-vessel lesion group,and the blood NT-proBNP and MHR in the triple-vessel lesion group were higher than those in the double-vessel lesion group,with statistically significant differences(P<0.05).QRS and ST segment depression were positively correlated with the number of coronary artery lesions in NSTEMI patients(P<0.05),while the number of ST segment depression leads and T wave inversion were not correlated with the number of coronary artery lesions in NSTEMI patients(P>0.05).The blood NT-proBNP and MHR were positively correlated with the number of coronary artery lesions in NSTEMI pa-tients(P<0.05).Conclusion The degree of QRS,ST segment depression,NT-proBNP,and MHR are positively correlated with the number of coronary artery lesions in NSTEMI patients.