奥曲肽和奥美拉唑治疗急性上消化道出血的研究进展

Research Progress on the Treatment of Emergency Upper Gastrointestinal Bleeding with Octreotide and Omeprazole

据统计,我国成人急性上消化道出血的年发病率在100/10万~180/10万。且大多患者在急诊科首次就诊时发现,病情大多危急。本病最常采用的方法为药物保守治疗,且以联合用药为主。奥曲肽和奥美拉唑是常用于治疗上消化道出血的联合用药方案,关于二药治疗情况的研究曾是相关研究领域的热点议题之一。本文介绍上消化道出血的病因和特点,总结急性上消化道出血的治疗现状,并分析了奥曲肽和奥美拉唑在急性上消化道出血中的联合治疗情况,以为内科保守治疗上消化出血提供用药依据。

According to statistics,the annual incidence of acute upper gastrointestinal bleeding in adults in our country is between 100/100,000 and 180/100,000.And most patients were diagnosed with such a disease during their first visit to the acute care department,while the condition was critical for most of them.The most commonly used treatment method for this disease is conservative drug treatment,and the combination of drugs is mainly used.Octreotide combined with omeprazole was commonly used combination,and the study on the treatment effect of the combination has become one of the hot topics in related research fields.This article introduced the etiology and characteristics of upper gastrointestinal bleeding,summarized the current treatment methods of emergency upper gastrointestinal bleeding,and analyzed the effect of combined treatment of octreotide and omeprazole in emergency upper gastrointestinal bleeding,so as to provide medication basis for conservative treatment of upper gastrointestinal bleeding in emergency internal medicine.