血清降钙素原、白细胞、血培养联合检测对急诊细菌感染性疾病的诊断价值

The Combined Detection Value of Serum Procalcitonin,White Blood Cells,and Blood Culture in the Diagnosis of Emergency Bacterial Infections

目的探讨血清降钙素原(PCT)、白细胞计数(WBC)、血培养联合检测对急诊细菌感染性疾病的诊断价值。方法选取2022年9月至2023年9月厦门市第三医院收治的90例急诊感染性疾病患者和同期进行体检的40例健康体检者为研究对象。根据病原学检查结果,将感染性疾病患者分为细菌感染组(50例)和病毒感染组(40例),并将健康体检者视为对照组。比较三组血清PCT水平、WBC及血培养其阳性情况,并比较PCT、WBC、血培养单独与联合检测在急诊细菌感染性疾病中的诊断价值。结果细菌感染组患者的血清PCT水平、PCT阳性率、WBC计数、WBC阳性率、血培养阳性率均高于病毒感染组和健康对照组,差异均有统计学意义(P值均<0.05);病毒感染组、健康对照组的血清PCT水平、PCT阳性率、WBC计数、WBC阳性率、血培养阳性率比较,差异无统计学意义(P>0.05)。PCT、WBC、血培养联合诊断的灵敏度(96.00%),准确度(97.50%),特异度(96.67%)、阳性预测值(97.96%)和阴性预测值(95.12%)均高于单独检测手段。结论PCT、WBC、血培养联合检测对急诊细菌感染性疾的诊断价值较高。

Objective To investigate the diagnostic value of serum procalcitonin(PCT),white blood cell count(WBC),and blood culture combined detection for the diagnosis of emergency bacterial infectious diseases.Methods 90 patients with emergency infectious diseases admitted to Xiamen Third Hospital from September 2022 to September 2023 and 40 health examinees who underwent physical examination at the same time were selected as research subjects.According to the results of pathogen examination,the patients with infectious diseases were divided into the bacterial infection group(n=50)and the viral infection group(n=40),with healthy individuals as the control group.The levels of serum PCT,WBC,and blood culture positivity were compared among the three groups,as well as the diagnostic value of PCT,WBC,blood culture alone and in combination in emergency bacterial infectious diseases.Results The levels of serum PCT,PCT positivity,WBC count,WBC positivity,and blood culture positivity in the bacterial infection group were higher than those in the viral infection group and the control group,with statistically significant differences(P<0.05).There were no statistically significant differences in the levels of serum PCT,PCT positivity,WBC count,WBC positivity,and blood culture positivity between the viral infection group and the control group(P>0.05).The sensitivity(96.00%),accuracy(97.50%),specificity(96.67%),positive predictive value(97.96%),and negative predictive value(95.12%)of the combined detection of PCT,WBC,and blood culture were higher than those of single detection methods.Conclusion Serum procalcitonin,white blood cell count,and blood culture combined detection have a high diagnostic value for emergency bacterial infectious diseases.