彩色多普勒超声血流信号及血流参数对原发性肝癌与转移性肝癌的诊断作用研究

Study on the Diagnostic Role of Color Doppler Ultrasound Blood Flow Signals and Parameters in Primary Liver Cancer and Metastatic Liver Cancer

目的:探讨彩色多普勒超声血流信号及血流参数对原发性肝癌及转移性肝癌的诊断价值。方法:对2021年1月-2023年6月韶关市曲江区人民医院体检中心科室收治的100例肝癌患者临床资料进行回顾性分析,所有患者均经病理组织确诊,其中原发性肝癌48例,转移性肝癌52例,所有患者均行彩色多普勒超声检查,比较两组血流信号、血流参数差异。结果:超声对原发性肝癌检出率为95.83%(46/48),与病理结果一致性较好(Kappa=0.715,P<0.05),超声对转移性肝癌检出率为88.46%(46/52),与病理结果一致性一般(Kappa=0.695,P<0.05);原发性肝癌组瘤周血流信号、瘤内血流信号检出率分别为93.75%(45/48)、91.67%(44/48),明显较转移性肝癌组75.00%(39/52)、67.31%(35/52)高(P<0.05);原发性肝动脉直径、门静脉流速、肝动脉峰值流速、肝动脉最小流速、RI各项超声血流参数与转移性肝癌组相比,有显著差异(P<0.05);原发性肝癌声像图多表现为形态不规则、大小不一,多为单发性病灶,边界清晰,超声显示为等或低回声;转移性肝癌大小、形态不一,多为等回声,边界清晰,呈“靶环征”。结论:彩色多普勒超声对原发性及转移性肝癌具有较高诊断价值,可精准反映两者血供分布情况,通过超声血流动力学参数可有效鉴别诊断两者,值得推广。

Objective:To explore the the diagnostic value of color Doppler ultrasound blood flow sig-nals and parameters for primary liver cancer and metastatic liver cancer.Methods:A retrospective analy-sis was conducted on the clinical data of 100 liver cancer patients admitted to the Physical Examination Center of Qujiang District People's Hospital in Shaoguan City from January 2021 to June 2023.All pa-tients were confirmed by pathological tissue examination,including 48 cases of primary liver cancer and 52 cases of metastatic liver cancer.All patients underwent color Doppler ultrasound examination to com-pare the differences in blood flow signals and parameters between the two groups.Results:The detection rate of primary liver cancer by ultrasound was 95.83%(46/48),which was consistent with the pathological results(Kappa=0.715,P<0.05).The detection rate of metastatic liver cancer by ultrasound was 88.46%(46/52),which was generally consistent with the pathological results(Kappa=0.695,P<0.05).The detec-tion rates of peritumoral blood flow signal and intratumoral blood flow signal in the primary liver cancer group were 93.75%(45/48)and 91.67%(44/48),respectively,which were significantly higher than 75.00%(39/52)and 67.31%(35/52)in the metastatic liver cancer group(P<0.05).There were significant differences(P<0.05)in the primary hepatic artery diameter,portal vein flow velocity,hepatic artery peak flow velocity,hepatic artery minimum flow velocity,and RI ultrasound blood flow parameters compared to the metastatic liver cancer group.Primary liver cancer ultrasound often presents as irregular shapes and varying sizes,mostly single lesions with clear boundaries,and ultrasound shows equal or low echogenicity.Metastatic liver cancer varies in size and shape,mostly with equal echogenicity and clear boundaries,pre-senting as a"target ring sign".Conclusion:Color Doppler ultrasound has high diagnostic value for primary and metastatic liver cancer,and can accurately reflect the blood supply distribution of the two.By using ul-trasound hemodynamic parameters,the two can be effectively differentiated and diagnosed,which is worth promoting.