表型组学时代下的人类遗传资源利用与管理的发展趋势

The development trends of utilization and management of human genetic resources in the era of phenomics

人类遗传资源是指可单独或联合用于识别人体特征的遗传材料与信息,包括所有来自于人体的样本以及基于样本产生的数据及相关信息,是生物医药研究与创新的重要基础,对揭示健康与疾病的人群规律至关重要,同时也是支撑疾病防控策略制定的关键资源,已成为关乎公众健康、生命安全的战略性、公益性和基础性资源.迈进表型组学的新时代,确保人类遗传资源的合法合规获取、有效管理、开发利用及共享,成为了科研工作中的核心议题.本文将从人类遗传资源管理现状、发展动态及其与表型组学的联系等几方面进行综述.

Human genetic resources refer to genetic material or information that can be used individually or collectively to identify human characteristics.This includes all samples derived from the human body,as well as the data and related information generated from human samples.Human genetic resources form an important material and information foundation for biomedical research,providing essential data for understanding and mastering the occurrence,development,and distribution patterns of diseases.They are also crucial for promoting the development of disease prevention,intervention,and control strategies.Therefore,human genetic resources have become strategic,public welfare,and fundamental resources for public health and life safety.With the advent of the phenomics era,it has become essential to assess the rational and legal acquisition,management,development,and sharing of human genetic resources in scientific research.This article provides a comprehensive review of the current status and development trends in the management of human genetic resources,as well as their connection to phenomics.