血细胞活库支撑血细胞图谱计划和生态研究

The living blood cells biobank supports atlas of blood cells project and blood ecosystem research

生物样本活库相较于传统生物样本库,对“血液生态”具有更高的研究利用价值.通过对血细胞活库的规范化建设,我们构建了“数据+样本+X”的一体化管理模式,为血细胞图谱计划提供坚实的资源支撑.率先建立单细胞水平全套造血细胞分子指纹图谱,并成功创建了精细完整的血细胞单细胞数据共享平台.这些进展不仅为血液生理及相关疾病的研究提供了宝贵的研究资源和公共分析工具,而且为疾病的精准诊断和治疗提供新策略.

Compared with traditional biobanks,the living biobank provides better support for“blood ecosystem”research.By standardized construction of the blood cell living biobank,a“data+sample+X”integrated management model was formed to provide support for the“atlas of blood cells”project,taking the lead in characterizing a complete set of molecular fingerprints of hematopoietic cells at the single-cell level,and establishing a refined blood single-cell data sharing platform,which provided valuable research resources and public analysis tools for research on blood physiology and related diseases,and new strategies for precise diagnosis and treatment.