富血小板血浆在卵巢低反应患者中的应用及研究进展

Application and research progress of platelet-rich plasma in patients with poor ovarian response

卵巢低反应(poor ovarian response,POR)是辅助生殖领域所面临的一大难题。富血小板血浆(platelet-rich plasma,PRP)作为一种新型治疗方法,已被证明在促进血管生成、细胞分化和增殖、卵泡生成等方面发挥着积极的作用,对于POR患者的治疗具有巨大的优势。本文就PRP的来源及制备、对POR患者卵巢功能和妊娠结局的影响以及PRP可能的作用机制进行综述。此外,文章还探讨了在POR患者治疗过程中PRP所面临的挑战以及未来可关注的研究方向,旨在为临床和科研工作者提供参考。

Poor ovarian response(POR)is a major challenge in the field of assisted reproduction.Platelet-rich plasma(PRP),as a new treatment,has been shown to have significant advantages in promoting angiogenesis,cell differentiation and proliferation,and follicle formation in the treatment of POR patients.This review provides a comprehensive summary of the source and preparation of PRP,the impact of PRP on ovarian reserve and pregnancy outcomes in POR patients,and the possible mechanisms of PRP action.Additionally,it discusses the challenges faced by PRP in the treatment of POR patients and future research directions that can be focused on,aiming to provide valuable insights for clinical and scientific researchers.