摘要
氘(Deuterium,D)是氢的稳定同位素,通过特定技术降低天然水中氘的含量,可获得低氘水(Deuterium Depleted Water,DDW)。体内外多项研究表明,饮用低氘水可增强机体抗氧化能力和免疫调节作用,发挥抗肿瘤效应,且无毒副作用、饮用方便。本文重点介绍低氘水的抗肿瘤机制及相关应用研究进展,以期为临床肿瘤辅助治疗提供新的制剂。
Deuterium(D)is a stable isotope of hydrogen.Deuterium depleted water(DDW)can be produced by specific techniques as reducing the deuterium content of natural water.Multiple studies in vivo and in vitro have shown that drinking DDW can enhance the body’s antioxidant capacity and immune regulation,playing an anti-tumor role.It is non-toxic and convenient to drink.This article focuses on the anti-tumor mechanism and related application research progress of DDW,in order to provide new formulations for clinical tumor adjuvant therapy.
作者
朱静
张晓懿
沈超
徐志红
陈伟
陈奕
ZHU Jing;ZHANG Xiaoyi;SHEN Chao;XU Zhihong;CHEN Wei;CHEN Yi(Department of Nuclear Medicine,Changshu No.2 People’s Hospital,Changshu 215500,China;State Key Laboratory of Radiation Medicine and Protection,Soochow University,Suzhou 215123,China;Suzhou Sicui Institute of Isotope Technology Co.,Ltd.,Changshu 215500,China)
出处
《生物化工》
CAS
2024年第3期199-203,共5页
Biological Chemical Engineering
基金
放射医学与辐射防护国家重点实验室资助项目(GZK1202109)
常熟市科技发展计划(社会发展)项目(CS202245)。
关键词
低氘水
抗肿瘤
作用机制
辅助治疗
deuterium depleted water
anti-tumor
functional mechanism
adjuvant therapy