摘要
心肌纤维化与多种心血管疾病(CVD)发生、发展密切相关,而成纤维细胞激活蛋白(FAP)在其中发挥关键作用。^(68)Ga-FAP抑制剂(FAPI)对FAP具有高亲和力及特异度,现已逐渐用于心血管PET显像。本文围绕^(68)Ga-FAPI PET显像用于CVD研究进展进行综述。
Myocardial fibrosis is closely related to the occurrence and development of various cardiovascular diseases(CVD),in which fibroblast activation protein(FAP)plays key roles.^(68)Ga-FAP inhibitors(FAPI)have high affinity and specificity for FAP,having been gradually applied to cardiovascular PET imaging.The research progresses of ^(68)Ga-FAPI PET imaging in cardiovascular diseases were reviewed in this article.
作者
林学智
张国建
LIN Xuezhi;ZHANG Guojian(The First Clinical Medical College of Inner Mongolia Medical University,Hohhot 010050,China;Department of Nuclear Medicine,the Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010050,China;Key Laboratory of Molecular Imaging,Inner Mongolia Autonomous Region,Hohhot 010050,China)
出处
《中国医学影像技术》
CSCD
北大核心
2024年第7期1096-1099,共4页
Chinese Journal of Medical Imaging Technology
基金
内蒙古科技成果转化专项(2019CG097)。
