个体化系统营养支持联合阶段式认知行为干预在食管癌放化疗患者中的应用

Effect of Individualized Systematic Nutritional Support Combined with Staged Cognitive Behavioral Intervention in Patients with Esophageal Cancer undergoing Chemoradiotherapy

目的:探讨个体化系统营养支持联合阶段式认知行为干预在食管癌放化疗患者中的应用效果。方法:选取2019年1月1日~2023年1月1日收治的150例食管癌放化疗患者作为研究对象,按照随机数字表法分为研究组和对照组各75例,对照组实施常规护理,研究组实施个体化系统营养支持联合阶段式认知行为干预;比较两组干预前后营养状况[包括血清血红蛋白(Hb)、前白蛋白(PA)、白蛋白(ALB)、总蛋白(TP)]、生活质量[采用欧洲癌症治疗研究组织生命质量测定量表(EORTC-QOL-C30)]、不良事件、自我护理能力[采用自我护理能力测定量表(ESCA)]、负性情绪[采用贝克抑郁自评量表(BDI)、焦虑敏感指数量表(ASI)、恐惧视觉模拟评分法(FAVS)],不良事件发生情况、满意度。结果:干预后,两组Hb、PA、ALB、TP、EORTC-QOL-C30、ESCA评分均优于干预前(P<0.05),且研究组优于对照组(P<0.01);干预后,两组BDI、ASI、FAVS评分均低于干预前(P<0.05),且研究组低于对照组(P<0.01);研究组不良事件发生率及满意度均优于对照组(P<0.05)。结论:个体化系统营养支持联合阶段式认知行为干预,能改善食管癌放化疗患者的营养状况和负性情绪,提高其自我护理能力和满意度,减少不良事件发生,从而提高患者生活质量。

Objective:To explore the effect of individualized systematic nutritional support combined with staged cognitive behavioral in-tervention in patients with esophageal cancer undergoing radiotherapy and chemotherapy.Methods:A total of 150 patients treated with che-moradiotherapy from January 1,2019 to January 1,2023 were selected,and randomly divided into a study group and a control group,with 75 cases in each group,using a random number table method.The control group received routine care,while the study group received indi-vidualized systematic nutritional support combined with staged cognitive behavioral intervention.The nutritional status including hemoglobin(Hb),prealbumin(PA),albumin(ALB),total protein(TP),quality of life using the European Organization for Research and Treatment of Cancer Quality of Life C-30(EORTC-QOL-C30),adverse events,self-care ability using the exercise of self-care agency(ESCA),negative emotions using the Beck depression inventory(BDI),Anxiety Sensitivity Index(ASI),fear visual analog scale(FAVS),and satisfaction were compared between two groups before and after intervention.Results:After intervention,the Hb,PA,ALB,TP,EORTC-QOL-C30,and ESCA scores of both groups were better than before intervention(P<0.05),and the study group was better than that of the control group(P<0.01).After intervention,the BDI,ASI,and FAVS scores of both groups were lower than before intervention(P<0.05),and the study group was lower than the control group(P<0.01).The incidence and satisfaction of adverse events in the study group were higher than those in the control group(P<0.05).Conclusion:Individualized systematic nutrition support combined with staged cognitive behavioral in-tervention can improve the nutritional status and negative emotions of esophageal cancer patients undergoing chemoradiotherapy,improve self-care ability and satisfaction,reduce the occurrence of adverse events,and improve the quality of life of patients.