季氏复方马齿苋液保留灌肠预防混合痔术后切口感染临床研究

Clinical Study on Retention Enema with JI's Compound Portulacae Herbal Solution for Prevention of Incision Infection After Mixed Hemorrhoid Surgery

目的:观察季氏复方马齿苋液预防混合痔术后切口感染的临床效果。方法:选取60例湿热下注或气滞血瘀的混合痔患者,采用随机数字表法分为对照组和试验组各30例。对照组给予0.5%甲硝唑氯化钠注射液保留灌肠,试验组给予季氏复方马齿苋液保留灌肠。比较2组术后体温、手术切口感染征象、血清白细胞介素-10(IL-10)水平以及临床疗效。结果:2组术后临床疗效均为100%。术后第2、3、4天,2组体温比较,差异均无统计学意义(P>0.05),且2组体温均处于正常范围,均未出现37℃以上的发热患者。术后,2组均无出现红、肿、热、痛及脓性分泌物等感染征象。术后第3天,试验组平均IL-10(1.32±1.30)pg/mL,对照组为(1.45±1.65)pg/mL,2组比较,差异无统计学意义(P>0.05)。结论:季氏复方马齿苋液和0.5%甲硝唑氯化钠注射液,在预防混合痔术后感染方面疗效肯定,并起到相近效果,患者均无出现感染、发热、发炎等征象。

Objective:To observe the clinical effect of JI's Compound Portulacae Herbal Solution for prevention of incision infection after mixed hemorrhoid surgery.Methods:A total of 60 cases of mixed hemorrhoid patients with traditional Chinese medicine syndrome types of damp-heat pouring downward or qi stagnation and blood stasis were selected and divided into the control group and the trial group according to the random number table method,with 30 cases in each group.The control group received the retention enema with 0.5%Metronidazole Sodium Chloride Injection,and the trial group was given the retention enema with JI's Compound Portulacae Herbal Solution.Postoperative body temperature,signs of surgical incision infection,serum interleukin-10(IL-10)levels,and clinical effects were compared between the two groups.Results:The postoperative clinical effective rates in the two groups were 100%.There was no significant difference in body temperature at 2,3,and 4 days after the surgery between the two groups(P>0.05),and both groups had normal body temperature and did not have a fever above 37°C.After the surgery,there were no signs of infection such as redness,swelling,heat,pain,or purulent secretions in the two groups.During the first three days after the surgery,the average level of IL-10 was(1.32±1.30)pg/mL in the trial group and(1.45±1.65)pg/mL in the control group,there being no significant difference(P>0.05).Conclusion:JI's Compound Portulacae Herbal Solution and 0.5%Metronidazole Sodium Chloride Injection have a certain curative effect and similar effects in preventing postoperative infection of mixed hemorrhoids.Patients did not show signs of infection,fever,inflammation,etc.