急性脑梗死老年患者轻度认知障碍发生的影响因素

Influencing Factors of Mild Cognitive Impairment in Elderly Patients with Acute Cerebral Infarction

目的:探讨老年急性脑梗死(ACI)患者轻度认知障碍(MCI)发生情况及影响因素.方法:选取2023年1月至2024年1月本院收治的106例老年ACI患者为研究对象.依据简易智力状态(MMSE)评分,将其分为MCI组(n=22)与无MCI组(n=84).收集两组患者临床资料,采用多因素非条件Logistic回归法分析老年ACI患者发生MCI的影响因素.结果:本研究纳入的106例老年ACI患者中,发生MCI者为22例,MCI发生率为20.75%(22/106).两组患者年龄,合并糖尿病、原发性高血压及高脂血症占比比较,差异均有统计学意义(P<0.05).采用多因素非条件Logistic回归分析结果显示,年龄,合并原发性高血压、糖尿病及高脂血症,均是导致老年ACI患者发生MCI的独立危险因素(OR>1,P<0.05).结论:年龄、合并原发性高血压、合并糖尿病及高脂血症是老年ACI患者MCI发生的独立危险因素,应重点关注高龄和合并基础疾病患者,并尽早制定对症治疗措施,降低ACI患者MCI发生率.

Objective:To explore the influencing factors of mild cognitive impairment(MCI)in elderly patients with acute cerebral infarction(ACI).Methods:A total of 106 elderly ACI patients admitted to our hospital from January 2023 to January 2024 were selected in this study.According to the mini mental state(MMSE)scores,they were divided into MCI group(n=22)and non-MCI group(n=84).The clinical data of patients were collected and the influencing factors of MCI in elderly ACI patients were analyzed.Results:The incidence of MCI was 20.75%(22/106)in 106 elderly ACI patients.There were significant differences in age,diabetes,primary hypertension and hyperlipidemia between the two groups(P<0.05).By multivariate unconditional logistic regression analysis,age,primary hypertension,diabetes and hyperlipidemia were the influencing factors of MCI in elderly ACI patients(OR>1,P<0.05).Conclusion:Age,primary hypertension,diabetes and hyperlipidemia are independent risk factors for MCI in elderly patients with ACI.Attention should be paid to elderly patients with chronic diseases,and corresponding measures should be developed as soon as possible to reduce the incidence of MCI.