补阳还五汤联合二龙戏珠针灸法对老年脑卒中患者的临床疗效

Clinical effects of Buyang Huanwu Decoction combined with Erlong Xizhu Acupuncture Method on elderly patients with stroke

目的考察补阳还五汤联合二龙戏珠针灸法对老年脑卒中患者的临床疗效。方法96例患者随机分为对照组和观察组,每组48例,对照组给予二龙戏珠针灸法,观察组在对照组基础上加用补阳还五汤,疗程1个月。检测神经功能指标(NIHSS评分、NDS评分)、Hcy、CysC、血管内皮功能指标(ET-1、NO、vWF)、颅内血流动力学指标(Vmean、R、DR)、血液流变学指标(WBLSV、WBHSV、FIB、HCT、EAI)、预后评估指标(mRS评分、BI评分)变化。结果治疗后,2组神经功能指标、Hcy、CysC、ET-1、vWF、R、DR、血液流变学指标、mRS评分降低(P<0.05),NO、Vmean、BI评分升高(P<0.05),以观察组更明显(P<0.05)。结论补阳还五汤联合二龙戏珠针灸法可降低老年脑卒中患者血清Hcy、CysC水平,改善血管内皮功能、颅内血流动力学、血液流变学指标,从而改善神经功能,促进预后。

AIM To investigate the clinical effects of Buyang Huanwu Decoction combined with Erlong Xizhu Acupuncture Method on elderly patients with stroke.METHODS Ninety-six patients were randomly assigned into control group(48 cases)for 1-month intervention of Erlong Xizhu Acupuncture Method,and observation group(48 cases)for 1-month intervention of both Buyang Huanwu Decoction and Erlong Xizhu Acupuncture Method.The changes in neurological function indices(NIHSS score,NDS score),Hcy,CysC,vascular endothelial function indices(ET-1,NO,vWF),intracranial hemodynamic indices(Vmean,R,DR),hemorheological indices(WBLSV,WBHSV,FIB,HCT,EAI)and prognosis assessment indices(mRS score,BI score)were detected.RESULTS After the treatment,the two groups displayed decreased neurological function indices,Hcy,CysC,ET-1,vWF,R,DR,hemorheological indices,mRS score(P<0.05),and increased NO,Vmean,BI score(P<0.05),especially for the observation group(P<0.05).CONCLUSION For the elderly patients with stroke,Buyang Huanwu Decoction combined with Erlong Xizhu Acupuncture Method can reduce serum Hcy,CysC levels,and improve vascular endothelial functions,intracranial hemodynamics,hemorheological indices,thus improve neurological functions and promote prognosis.