凝血即时检验技术应用进展

Progress in application of blood coagulation point-of-care testing

凝血功能即时检验(POCT)不受场地限制,具有便于携带、操作简单、检测快速等优点。目前,POCT凝血仪采用的方法学主要有电化学法、生物传感器法、免疫化学法、机械法,它们具有各自的特点和优势,已逐渐应用于凝血常规、凝血因子、血小板功能检测和抗凝监测。文章对凝血POCT检测技术的原理、特点,以及应用现状、前景进行综述。

Point-of-care testing(POCT)refers to the fact that it can not be limited by places,which has the advantages of easy carrying,simple operation and rapid determination.At present,the methods used in POCT blood coagulation instrument mainly include electrochemical method,biosensor method,immunochemical method and mechanical method and so on,which have their own characteristics and advantages,and they are gradually applied to blood coagulation routine test,coagulation factor determination,platelet function determination and anticoagulation monitoring.This review focuses on the principles,characteristics,application status and prospects of blood coagulation POCT technology at home and abroad.