可见光诱导的二氧化碳对活化烯烃的脱碳羧基化反应

Visible Light-Induced Decarbon-Carboxylation of Activated Alkenes by Carbon Dioxide

报道了一种高效的可见光促进的活化烯烃脱碳羧化的方法,与传统的烯烃羧化相比,该方法条件温和,收率最高可达96%,对多种官能团具有很好的兼容性,为芳基乙酸的合成及后续转化提供了新方法.机理研究表明,该反应是通过对烯烃碳碳双键的置换,实现了表观碳数不变的对应羧酸的合成.

An efficient visible light-facilitated decarbon-carboxylation of activated alkenes has been successfully developed.Compared with traditional alkene carboxylation,this method features mild conditions,up to 96%yield and good compatibility with a variety of functional groups.It provides a new method for the synthesis of phenylacetic acid and its derivatives.The mechanism study shows that the reaction realizes the synthesis of the corresponding carboxylic acid with constant apparent carbon number by substituting the carbon-carbon double bond of alkene.