多发性骨髓瘤患者运动干预的最佳证据总结

Best evidence summary for exercise intervention in patients with multiple myeloma

目的评价并总结多发性骨髓瘤患者运动干预的相关证据,为临床医护人员指导多发性骨髓瘤患者运动提供借鉴。方法按“6S”模型系统检索国内外数据库关于多发性骨髓瘤患者运动干预的文献并进行质量评价及证据提取和汇总。结果共纳入10篇文献,包括3篇指南、1篇推荐实践、2篇系统评价、4篇随机对照试验。从运动前评估、运动时机和方式、运动强度和时间、方案制定原则、运动指导监督及注意事项总结出24条最佳证据。结论本研究以循证为基础总结了多发性骨髓瘤患者运动干预的最佳证据,包括运动评估、运动时机和方式、运动强度和时间共6个方面,为医护人员进行临床应用提供循证依据,应用时需根据具体情境进行个体化调整。

Objective To evaluate and summarize the evidence related to exercise intervention in patients with multiple myeloma,and to provide reference for clinical staff to guide exercise in patients with multiple myeloma.Methods The literature on exercise intervention in patients with multiple myeloma was systematically searched according to the"6S"model,and the quality evaluation and evidence extraction and summary were carried out.Results A total of 10 articles were collected,including 3 guidelines,1 recommended practice,2 systematic reviews,and 4 randomized controlled trials.Twenty-four pieces of best evidence were summarized from six aspects:pre-exercise assessment,exercise timing and mode,exercise intensity and time,protocol development principles,exercise guidance and supervision and precautions.Conclusion The best evidence for exercise intervention in patients with multiple myeloma covers six aspects of exercise assessment,exercise timing and mode,exercise intensity and time,protocol development principles,exercise guidance and supervision and precautions.It can provide evidence-based basis for clinical practice,and the application needs to be individualized according to specific situation.