CT图像纹理参数对肺结节良恶性的鉴别诊断价值

The Differential Diagnostic Value of CT Image Texture Parameters for Benign and Malignant Pulmonary Nodules

目的探究CT图像纹理参数对良恶性肺结节(PN)的鉴别诊断价值。方法回顾性分析2021年3月至2023年12月医院收治的97例PN患者的病历资料。97例患者均经病理学检查确诊,55例恶性PN患者作为恶性组,42例良性PN患者作为良性组。两组入院时均接受CT检查,并进行CT图像纹理参数分析。比较两组的CT图像纹理参数,采用受试者工作特征(ROC)曲线评价CT图像纹理参数对良恶性PN的鉴别诊断价值。结果恶性组的CT图像纹理能量、熵、熵和、熵差均高于良性组,差异有统计学意义(P<0.05);两组的CT图像纹理对比度、相关性比较,差异均无统计学意义(P>0.05)。ROC分析结果显示,能量、熵、熵和、熵差单独及联合鉴别诊断良恶性PN的曲线下面积(AUC)均>0.70,均有一定诊断价值,且当各参数截断值分别取0.805、1.585、0.210、1.005时,可获得最佳诊断价值。结论CT图像纹理参数中能量、熵、熵和、熵差均对良恶性PN具有一定鉴别诊断价值。

Objective To explore the differential diagnostic value of CT image texture parameters for benign and malignant pulmonary nodules(PN).Methods With the retrospective analysis of the medical records of 97 PN patients admitted to the hospital from March 2021 to December 2023,97 patients were diagnosed through pathological examination,with 55 patients with malignant PN as the malignant group and 42 patients with benign PN as the benign group.Both groups of patients underwent CT examination on admission,and the texture parameters of CT images were analyzed.With the comparison of the texture parameters of CT images from two groups,the Receiver Operating Characteristic(ROC)curve was used to evaluate the differential diagnostic value of CT image texture parameters for benign and malignant PN.Results The texture energy,entropy,entropy sum,and entropy difference of CT images in the malignant group were higher than those in the benign group,and the differences were statistically significant(P<0.05);There were no statistically significant differences in texture contrast and correlation between the two groups of CT images(P>0.05).The ROC analysis results showed that the area under the curve(AUC)of energy,entropy,entropy sum,and entropy difference for individual and combined differential diagnosis of benign and malignant PN were all greater than 0.70,indicating certain diagnostic value.The best diagnostic value could be obtained when the cutoff values of each parameter were 0.805,1.585,0.210,and 1.005,respectively.Conclusion The energy,entropy,entropy sum and entropy difference of the texture parameters of CT images have certain value in the differential diagnosis of benign and malignant PN.