麦角硫因的功能、制备及应用研究进展

Research Progress on the Functions,Preparation and Application of Ergothioneine

麦角硫因(EGT)是一种天然的小分子组氨酸硫脲衍生物,存在于微生物细胞和动植物体内。EGT可由真菌、蓝细菌、放线菌等微生物合成,人体自身不能合成EGT,需通过饮食摄取,食用菌是EGT的重要饮食来源之一。EGT具有抗氧化、抗炎、免疫调节等多种生物学功能,在食品、药品和化妆品等领域具有广泛的应用。本文综述了EGT的生物学功能、制备方法及其应用的研究进展。

Ergothioneine(EGT)is a natural small molecule histidine thiourea derivative which exists in microbial cells,animals and plants.EGT can be synthesized by microorganisms such as fungi,cyanobacteria,and actinomycetes.The human body cannot synthesize EGT itself,and must obtain it through dietary intake.Edible fungi are one of the important dietary sources of EGT.EGT exhibits various biological functions such as anti-oxidation,anti-inflammation and immune regulation,and is widely used in the fields of food,drugs and cosmetics.This paper reviews the biological functions,preparation methods and applications of EGT.