基于中医传承辅助平台挖掘中药治疗认知障碍组方规律

The Prescription Rules of Traditional Chinese Medicine in the Treatment of Cognitive Impairment Based on the Traditional Chinese Medicine Inheritance Auxiliary Platform

目的:探究中药治疗认知障碍组方规律及用药特色。方法:以中国知网(CNKI)为数据来源,使用中医传承辅助平台(V2.5)分析近5年中药治疗认知障碍的组方规律。结果:根据检索、整理、分析,总结出相关方剂151首、中药188味,高频用药6味,常用药对8对,用药规则5条,潜在新方8首;治疗认知障碍药物以滋阴补肾、化痰开窍、祛瘀化湿为主;四气以温最多,五味以甘最多,归经以肝经最多。结论:用数据挖掘方法可以客观呈现中药治疗认知障碍的用药规律,为临床治疗和新药研发提供资料。

Objective:To explore the prescription rules and medication characteristics of traditional Chinese medicine in the treatment of cognitive impairment.Methods:Taking China National Knowledge Infrastructure(CNKI)as the data source,the traditional Chinese medicine inheritance support platform(V2.5)was used to analyze the prescription rules of traditional Chinese medicine in the treatment of cognitive impairment in the past five years.Results:According to the retrieval,collation and analysis,151 prescriptions,188 traditional Chinese medicines,6 high-frequency medicines,8 pairs of commonly used medicines,5 medication rules and 8 potential new prescriptions were summarized.The drugs for treating cognitive impairment were mainly nourishing yin and tonifying kidney,resolving phlegm and opening orifices,removing blood stasis and dampness.The four qi was the most warm,the five flavors were the most sweet,and the liver meridian was the most meridian.Conclusion:Data mining method can objectively present the medication rules of traditional Chinese medicine in the treatment of cognitive impairment,and provide ideas for clinical treatment and new drug research and development.