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Emerging tropane alkaloids:Global development and potential health threats

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摘要 Tropane alkaloids(TAs)are a kind of plant secondary metabolite that mainly originate from Solanaceae.They have potent anticholinergic activity,and are well-known anticholinergic drugs,but have also been reported as plant toxins.Many studies have been conducted on TAs,but no scientometric research has been performed.This study aimed to expound the knowledge network and development of the feld of TAs and predict the emerging development topics based on bibliometrics.In particular,this research combined VOSviewer and CiteSpace for visualization and covered 1,298 related scientifc publications(1953–2022).The research on TAs is rapidly developing,with the participation of 86 countries,1,129 research institutions,and 4,087 researchers.China,the University of Geneva,and P.Christen are the most productive country,institution,and researcher,respectively.Currently,the main research topics on TAs include biosynthesis,in vitro synthesis,chemical synthesis,and determination methods.Since 2018,the monitoring of TAs in food related to human health has shown citation burst characteristics,which is considered an emerging development trend in the future.The fndings of this study will enable researchers to quickly tap into the knowledge background/structure of TAs from massive data to provide a reference for further research.
出处 《Food Quality and Safety》 SCIE CAS CSCD 2024年第1期12-26,共15页 食品品质与安全研究(英文版)
基金 the Ministry of Science and Technology of the People’s Republic of China(No.2020YFF01014605).
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