500张高血压处方点评及用药合理性分析

500 Hypertension Prescription Reviews and Rational Analysis of Drug Use

目的:点评本院500张高血压处方并分析用药合理性。方法:回顾性分析广州医科大学附属第二医院2023年1—6月开具的高血压处方500张,对其进行处方点评及合理性分析,统计患者年龄分布情况、处方药物组成及用药不合理情况。结果:>60~80岁患者299例,占比最高(59.80%);27~40岁患者7例,占比最低(1.40%)。>40~60岁患者123例,占24.6%;>80~100岁患者71例,占14.2%。常见药物包括富马酸比索洛尔片、盐酸乐卡地平片、瑞舒伐他汀钙片、阿托伐他汀钙片、硫酸氢氧吡格雷片、奥美沙坦酯片、铝镁匹林片、琥珀酸美托洛尔片、沙库巴曲缬沙坦钠片和复方血栓通胶囊。富马酸比索洛尔片占比最高,为19.53%;复方血栓通胶囊为辅助用药,占比最低,为5.51%。500张处方中共有不合理处方73张,包括用法用量不合理、适应证不合理、用药价格不合理、未写第2类精神药品标志、不良相互作用以及重复用药。结论:通过对500张高血压处方的点评和用药合理性分析,发现存在一定比例的不合理处方。临床需要进一步加强用药合理性的评估和指导,确保患者的治疗效果和用药安全性。

Objective:To review 500 hypertension prescriptions in the hospital and analyze the rationality of drug use.Methods:A retrospective analysis was made on five hundred hypertension prescriptions issued by the Second Affiliated Hospital of Guangzhou Medical University from January to June 2023,and the prescription comments and rationality analysis were carried out to analyze the age distribution of patients,prescription drug composition and irrational drug use.Results:There were 299 patients aged>60-80 years,accounting for the highest proportion(59.80%);there were 7 patients aged 27-40 years,accounting for the lowest proportion(1.40%).There were 123 patients aged>40-60 years,accounting for 24.6%;there were 71 patients aged>80-100 years,accounting for 14.2%.Common drugs include bisoprolol fumarate tablets,lecardipine hydrochloride tablets,rosuvastatin calcium tablets,atorvastatin calcium tablets,hydropidogrel sulfate tablets,olmesartan acetate tablets,aluminum magnesium pirin tablets,metoprolol succinate tablets,sacubactril valsartan sodium tablets,and compound Xueshuantong capsules.Bisoprolol fumarate tablets accounted for the highest proportion(19.53%);compound Xueshuantong capsules was the adjuvant drug,accounting for the lowest proportion(5.51%).There were 73 unreasonable prescriptions out of 500 prescriptions,including unreasonable usage and dosage,unreasonable indications,unreasonable drug price,no sign of class 2 psychotropic drugs,adverse interaction and repeated drug use.Conclusion:Through the review and rational analysis of 500 hypertension prescriptions,it was found that there was a certain proportion of irrational prescriptions.Clinical need to further strengthen the evaluation and guidance of the rationality of drug use to ensure the therapeutic effect and drug safety of patients.