吲哚菁绿荧光显影导航技术在胆囊切除术中的应用价值

Application Value of Indocyanine Green Fluorescence Imaging Navigation Technique in Cholecystectomy

目的:探究吲哚菁绿荧光显影导航技术在胆囊切除术中的应用效果。方法:选取2022年5月—2023年5月凉山彝族自治州第一人民医院收治的胆囊切除术患者80例作为研究对象,随机将患者分为观察组与对照组,各40例。对照组实施常规腹腔镜术治疗,观察组实施吲哚菁绿荧光显影导航技术下腹腔镜术治疗。比较两组手术指标、术中情况、炎性因子水平及术后并发症发生情况。结果:观察组手术时间、住院时间、明确胆管系统时间、胃肠道功能恢复时间短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05);观察组肝外胆管识别等级优于对照组,观察组胆囊三角暴露时间短于对照组,差异有统计学意义(P<0.05);两组放置引流管、中转开腹率比较,差异无统计学意义(P>0.05);治疗后,两组白细胞介素-21、白细胞介素-22及转化生长因子-β1水平低于治疗前,观察组低于对照组,差异有统计学意义(P<0.05);观察组术后并发症发生率低于对照组,差异有统计学意义(P<0.001)。结论:吲哚菁绿荧光显影导航技术可以有效缩短胆囊切除术手术时间,减少术中出血量和提高肝外胆管识别等级,降低术后炎性因子水平及并发症发生率。

Objective:To explore the application effect of indocyanine green fluorescence imaging navigation technique in cholecystectomy.Methods:A total of eighty patients with cholecystectomy admitted to Liangshan Yi Autonomous Prefecture First People's Hospital from May 2022 to May 2023 were selected as the study objects,and randomly divided into observation group and control group,with forty patients in each group.The control group was treated with conventional laparoscopy,and the observation group was treated with indocyanine green fluorescence imaging navigation technology.The operative indexes,intraoperative conditions,inflammatory factors and postoperative complications were compared between the two groups.Results:The operation time,hospital stay time,clear bile duct system time and gastrointestinal function recovery time in observation group were shorter than those in control group,and the intraoperative blood loss was less than that in control group,the difference was statistically significant(P<0.05);the recognition level of extrahepatic bile duct in the observation group was better than that in the control group,and the exposure time of gallbladder triangle in the observation group was shorter than that in the control group,the difference was statistically significant(P<0.05);there was no significant difference in the rate of drainage tube placement and conversion to laparotomy between the two groups(P>0.05);after treatment,the levels of interleukin-21,interleukin-22 and transforming growth factor-β1 of the two groups were lower than before treatment,and the observation group was lower than control group,the difference was statistically significant(P<0.05);the incidence of postoperative complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.001).Conclusion:Indocyanine green fluorescence imaging navigation technology can effectively shorten the operation time of cholecystectomy,reduce the amount of intraoperative blood loss,improve the level of extrahepatic bile duct recognition,reduce the level of postoperative inflammatory factors and the incidence of complications.