摘要
胆汁酸不仅在调节脂类代谢中发挥着关键的生理作用,而且也参与调节中枢神经系统。大量研究表明,胆汁酸代谢异常与抑郁症之间关系密切,但具体的机制尚不清楚。本文旨在总结胆汁酸代谢和抑郁症之间的关系,为抑郁症的研究及治疗提供新的视角。
Bile acids not only play an important physiological role in regulating lipid metabolism,but also participate in the regulation of central nervous system.Numerous studies indicated that abnormal bile acid metabolism is closely related to depression,but the exact mechanism remains unclear.This study summarized the relationship between bile acid metabolism and depression and aimed to provide a new perspective for the study and treatment of depression.
作者
刘辉
汪保英
许二平
白明
沈继朵
栗俞程
LIU Hui;WANG Baoying;XU Erping;BAI Ming;SHEN Jiduo;LI Yucheng(Henan Collaborative Innovation Center for Research and Development on the Whole Industry Chain of Yu-Yao,Zhengzhou 450046,China;Henan Key Laborary for Modern Research on Zhongjing's Herbal Formulae,Academy of Chinese Medical Sciences,Henan University of Chinese Medicine,Zhengzhou 450046,China;College of Pharmacy,Henan University of Chinese Medicine,Zhengzhou 450046,China)
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2024年第7期1351-1355,共5页
Chinese Journal of Pathophysiology
基金
河南省自然科学基金资助项目(No.202300410249)。
关键词
抑郁症
胆汁酸
肠道菌群
depression
bile acids
gut microbiota
