便携式血液净化设备的前世今生

Past and present of portable blood purification devices

血液净化不仅是急慢性肾衰竭患者的有效治疗手段,也在各类危重症患者的抢救中发挥了重要作用。目前的血液净化设备较为笨重,不适合在日常生活和灾害救援现场使用。便携式血液净化设备可分为便携式血液透析机、可穿戴式血液透析机、植入式人工肾和便携式连续性肾脏替代治疗机等类型,但均尚未在临床上得到大规模应用。近年来随着材料科学和计算机科学的进步,透析液的高效再生和设备的智能化运行成为可能,便携式血液净化设备也有望迎来快速发展。该文将简要阐述便携式血液净化设备的发展历程和未来研究方向。

Blood purification is not only an effective treatment for patients with acute and chronic renal failure,but also plays an important role in the rescue of various critically ill patients.The current blood purification devices is relatively bulky and not suitable for use in daily life and disaster rescue sites.Portable blood purification devices can be divided into portable artificial kidney,wearable artificial kidney,implantable artificial kidneys and mobile continuous renal replacement therapy machine,which have not yet been widely applied in clinical practice.In recent years,with the advancement of materials science and computer science,efficient regeneration of dialysate and intelligent operation of equipment have become possible,and portable blood purification devices is also expected to experience rapid development.This article briefly reviews the development history and future research directions of portable blood purificationdevices.