握力与主观认知下降在不同性别维持性血液透析患者中的相关性分析

`Correlation analysis between grip strength and subjective cognitive decline in maintenance hemodialysis patients of different genders

目的探讨握力在不同性别维持性血液透析(maintenance hemodialysis,MHD)患者中与主观认知下降(subjective cognitive decline,SCD)的相关性。方法选取在四川大学华西医院肾脏内科温江血液透析室2024年3月-6月进行门诊MHD的患者作为研究对象。采用多重线性回归分析探讨握力在不同性别MHD患者中与SCD的关系。结果共调查患者171例,非SCD组76例,SCD组95例。多重线性回归分析结果显示,文化程度(P=0.039)、营养状况(P=0.026)、握力(P=0.042)是男性MHD患者SCD的影响因素;工作状态(P=0.001)、营养状况(P=0.011)是女性MHD患者SCD的影响因素。结论文化程度、营养状况及握力是男性MHD患者SCD的影响因素;工作状态及营养状况是女性MHD患者SCD的影响因素。握力或可作为评估男性MHD患者SCD的一项指标。

Objective To investigate the correlation between grip strength and subjective cognitive decline(SCD)in maintenance hemodialysis(MHD)patients of different genders.Methods Patients who underwent outpatient MHD in the Wenjiang Hemodialysis Unit,Department of Nephrology,West China Hospital,Sichuan University between March and June 2024 were selected as the research subjects.Multiple linear regression analysis was used to explore the relationship between grip strength and SCD in MHD patients of different genders.Results A total of 171 patients were investigated,with 76 in the non-SCD group and 95 in the SCD group.The results of multiple linear regression analysis showed that educational level(P=0.039),nutritional status(P=0.026),and grip strength(P=0.042)were the influencing factors of SCD in male MHD patients.Work status(P=0.001)and nutritional status(P=0.011)were the influencing factors of SCD in female MHD patients.Conclusions Educational level,nutritional status,and grip strength are influencing factors of SCD in male MHD patients.Work status and nutritional status are influencing factors of SCD in female MHD patients.Grip strength may serve as an indicator for evaluating SCD in male MHD patients.