液基细胞学检查及人乳头状瘤病毒检测与阴道镜检查在宫颈癌前病变和宫颈癌筛查中的应用价值

The Application Value of LBC and HPV Detection and Colposcopy in Cervical Precancerous Lesions and Cervical Cancer Screening

目的:分析探讨液基细胞学检查(LBC)及人乳头状瘤病毒(HPV)与阴道镜检查在宫颈癌前病变和宫颈癌筛查中的应用价值。方法:本次将本中心2022年1月~2023年8月行宫颈癌筛查的疑似宫颈癌前病变患者纳入研究,依次行LBC、HPV、阴道镜检查,以病理结果为“金标准”,对LBC及HPV检测与阴道镜检查的价值效果进行分析评价。结果:①以病理结果为“金标准”,LBC、HPV、阴道镜、LBC+HPV+阴道镜检查结果准确率分别80.00%、86.00%、90.00%、98.00%,联合检查与单独检查两两对比差异明显,有统计学意义(P<0.05)。②LBC+HPV+阴道镜检查结果与病理结果基本一致,对比无明显差异(P>0.05)。结论:在宫颈癌前病变和宫颈癌筛查中,LBC+HPV检测+阴道镜检查的诊断符合率高,与病理结果基本一致,可减少漏诊、误诊的发生,为宫颈癌预防、早期治疗提供有效参考凭据。

Objective:To analyze the application value of liquid-based cytology(LBC),human papillomavirus(HPV)and colposcopy in screening of cervical precancerous lesions and cervical cancer.Methods:Patients with suspected cervical precancerous lesions who received cervical cancer screening from January 2022 to August 2023 in our center were included in the study.LBC,HPV and colposcopy were performed in turn,and the value and effect of LBC and HPV detection and colposcopy were analyzed and evaluated with pathological results as the“gold standard”.Results:①Taking pathological results as the“gold standard”,the accuracy of LBC,HPV,colposcopy,LBC+HPV+colposcopy results was 80.00%,86.00%,90.00%,98.00%,respectively,and the pair-based comparison between combined examination and single examination was significant,with statistical significance(P<0.05).②The results of LBC+HPV+colposcopy were basically consistent with the pathological results,and there was no significant difference in comparison(P>0.05).Conclusion:In the screening of cervical precancerous lesions and cervical cancer,the diagnosis coincidence rate of LBC+HPV+colposcopy is high,which is basically consistent with the pathological results,can reduce the occurrence of missed diagnosis and misdiagnosis,and provide effective reference for the prevention and early treatment of cervical cancer.